Week 10 Monday Night Football Odds: Eagles vs Packers

NFL
November 8, 2025

Eagles vs Packers

 

NFL Odds: Philadelphia Eagles vs Green Bay Packers Prediction, Monday Night Football Week 10

 

The Monday Night Football spotlight turns to Lambeau Field as the 6-2 Philadelphia Eagles visit the 5-2-1 Green Bay Packers on November 10, 2025. NFL Odds at BUSR have the Packers favored by 2.5 points, with the total set at 45.5. 

The matchup features two division leaders who rely on balance and late-game efficiency, setting up one of the most anticipated primetime games of Week 10. This breakdown covers both teams’ profiles, statistical edges, betting trends, and the strongest wagering approach for NFL Betting this week.

 

Green Bay Packers Overview

 

Green Bay sits first in the NFC North at 5-2-1, maintaining a 3-1 record at Lambeau Field. Despite a 13-16 loss to Carolina, the Packers remain one of the most efficient two-way teams in football. Their offense ranks 11th in scoring, averaging 25.8 points per game, and 360.4 total yards per contest. 

 

Packers Offensive

Jordan Love leads an attack that generates 247.5 passing yards and 112.9 rushing yards per game. His efficiency is on the rise, with a 70.8% completion rate, 2,071 yards, and 13 touchdowns through eight games.

Josh Jacobs continues to provide balance in the backfield, rushing for 534 yards while averaging over 75 total yards in each of his last eight November appearances against NFC opponents. His consistency in the passing game adds another 17+ receiving yards per contest, and he has scored at least one touchdown in each of Green Bay’s last 13 games versus NFC opponents. 

Tight end Tucker Kraft has emerged as a reliable weapon, leading the team with 489 receiving yards and six touchdowns on 32 receptions.

 

The Green Bay Defensive Edge

Defensively, Green Bay remains disciplined and opportunistic. The unit ranks 8th in scoring defense, allowing 20.8 points per game, and gives up only 286.4 yards per outing. They have tightened up against the run, limiting opponents to 89.4 rushing yards, while their pass defense holds quarterbacks to 197 yards per game. 

Linebacker Quay Walker leads with 71 tackles, and Rashan Gary has posted 7.5 sacks, anchoring the league’s most productive fourth-quarter defense at 12.0 points per game. Xavier McKinney’s two interceptions highlight a secondary that thrives on field position and closing speed.

From a betting perspective, the Packers are 3-5 against the spread (ATS) and 3-4-1 to the Over/Under. At home, they’ve been profitable late in games, they’ve won each of their last six Monday home contests, and consistently scored first, opening every one of their last ten games as favorites against NFC East teams with an opening touchdown. The first-quarter data also leans toward Green Bay: the Packers have taken the first-quarter lead in four of their last five games against winning teams, indicating strong preparation out of the gate.

 

 

Philadelphia Eagles Overview

 

The Eagles enter at 6-2, first in the NFC East, and they’ve covered the spread in five of their eight games. Philadelphia is coming off a 38-20 win over the New York Giants and looks to extend its dominance against NFC North opponents, having won nine straight against that division. Their offense averages 26.0 points per game, ranking 10th, with 304.4 yards of total offense. That production splits into 192.8 passing and 111.6 rushing yards per game.

 

The Offense set to Flight High

Jalen Hurts leads the way with 1,677 passing yards, completing 70.2% of his throws with 15 touchdowns. He remains a red-zone threat, scoring in each of the Eagles’ last seven Monday night regular-season games. 

The backfield features Saquon Barkley, who has 519 rushing yards and has scored multiple touchdowns in three of his last four November appearances against NFC opponents. Rookie Tank Bigsby has complemented him with consistent short-yardage gains, topping 28 rushing yards in six straight appearances as an underdog.

DeVonta Smith continues to headline the receiving corps, catching 44 passes for 588 yards and two touchdowns. Smith has topped 73 yards in six straight games as a road underdog, and the offense’s versatility is evident: four different players have recorded multi-touchdown games this season, tied for most in the league. Philadelphia also leads the NFL with two different players who have rushed for 80+ yards in a game, underscoring their balanced attack.

 

Offense to Tackle the Ground Game

Defensively, the Eagles allow 23.1 points per game (19th), surrendering 336.3 yards of total offense. They’ve struggled against the run, allowing 120.4 yards per game, but their pass defense has held firm, yielding 215.9 yards. 

Zack Baun leads the team in tackles (64), Moro Ojomo paces the defense with four sacks, and Andrew Mukuba has picked off two passes. Hurts’s ability to control tempo offsets defensive lapses; the Eagles rank among the league’s best in first-half performance, having led at halftime in nine of their last ten games against winning teams.

For bettors, Philadelphia has been a strong primetime performer, covering in seven of their last eight Monday matchups against opponents with winning records. They’ve also scored first in 13 of their last 14 games after a win and have led after the opening quarter in eight of their last nine against winning teams. 

However, recent November history is less favorable: the Eagles have lost six straight November games as underdogs against NFC opponents and failed to cover in seven of their last eight November road games in that same role.

 

 

Key Statistical and Betting Angles

 

The NFL Odds show Green Bay favored by 2.5 points (-105) and Philadelphia at +2.5 (-115), reflecting a razor-thin market edge. The Packers’ moneyline sits at -130, while the Eagles are priced at +110. The total of 45.5 has drawn mixed signals; seven of Philadelphia’s last eight games against NFC opponents have gone Over, but each of Green Bay’s last five Week 10 home games as favorites has gone Under. 

The Lambeau environment has historically leaned toward the Under, with four of the last five Monday contests finishing below the total.

Player prop trends reveal clear usage patterns. For Green Bay, Jordan Love has surpassed 261 passing yards in seven of his last eight November games, and he has completed 21 or more passes in four of his previous five November home appearances. 

Jacobs remains a touchdown machine, finding the end zone in 13 consecutive games against NFC teams, and his workload projects well against Philadelphia’s 19th-ranked scoring defense.

Philadelphia’s prop indicators highlight Jalen Hurts’ dual-threat ceiling. He’s recorded at least one touchdown in seven consecutive Monday games and topped 221 passing yards in four of his last five contests as a slight underdog. 

Barkley has been a finisher in this spot, scoring the final touchdown in three of his last four games as an underdog versus NFC North opponents. With multiple explosive players, the Eagles are built to match Green Bay’s production pace, and their trendline toward Overs in NFC play supports offensive confidence.

 

Team and League Context

 

Both teams rank among the league’s best in situational scoring. Green Bay leads the NFL in fourth-quarter points at 12.0 per game, a key factor in closing spreads when holding slim leads. Philadelphia, on the other hand, thrives early; they’ve led after the first quarter in eight of their last nine games against winning teams. This dynamic sets up a live-betting opportunity: a first-half play on Philadelphia paired with a full-game lean toward Green Bay aligns with recent game flow data.

Special teams could also shape the cover margin. Green Bay ranks 32nd in average punt return yardage (4.9), giving up hidden field position that may keep Philadelphia’s offense in shorter fields. However, Lambeau’s November conditions favor teams that win the ground battle, and the Packers’ 89.4 rushing yards allowed per game suggest they can neutralize Barkley’s impact enough to dictate tempo.

The head-to-head history tilts slightly in Philadelphia’s favor, as the team has gone 4-1 in the last five meetings. However, the past four meetings in Green Bay are split 2-2. Favorites have covered in each of the previous four matchups, reinforcing the alignment between market expectation and outcome. The Packers’ strong record at home on Monday nights and the Eagles’ struggles as underdogs in November both support the case for the home side to win outright.

For totals bettors, recent combined scoring averages provide a compelling angle. These teams combine for 51.8 points per game and have produced an 8-2-1 record to the Over in their last 11 combined appearances. While Lambeau’s late-season climate typically pushes totals down, both teams’ offensive efficiency and red-zone diversity favor a high-scoring game that challenges the 45.5 threshold.

 

Betting Recommendation and Pick

 

NFL Betting for Monday Night Football centers on whether the Packers’ balanced offense and home-field efficiency can outlast Philadelphia’s quick-strike attack. Green Bay’s edge lies in quarterback stability, a consistent running game, and defensive discipline in the red zone. The Packers have covered their last six Monday home games, while the Eagles have repeatedly fallen short as road underdogs in November.

Jalen Hurts’ ability to extend plays and keep the chains moving gives the Eagles life in any environment. Still, the Packers’ ability to limit rushing yards and win possession time in cold conditions aligns with the spread. With Jordan Love’s rhythm at home and Jacobs’ ability to close drives, Green Bay projects as the more sustainable side across four quarters.

The “Totals” analysis contradicts the weather narrative. Seven of the Eagles’ last eight NFC games have gone Over, and both teams combine for more than 50 points per contest this season. Green Bay’s top-ranked fourth-quarter scoring profile supports a late push to clear the number, especially if both offenses trade touchdowns in the red zone.

The smart angle is to back Green Bay at -2.5 before the number reaches three and to play Over 45.5 for those expecting another primetime shootout. Both defenses are competent, but their offensive playmakers are more reliable in high-leverage situations.


Best Bets: Packers -2.5 and Over 45.5

 

 

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