NFL Picks: Week 10 Colts vs Patriots


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When the Indianapolis Colts and the New England Patriots face off in week 10 NFL action at Frankfurt Stadium, fans and bettors alike can expect a riveting showdown. With both teams eager for a victory after a series of losses, this game is critical to their season’s momentum.


Spread: Colts -1.5 (-110), Patriots +1.5 (-110) 

Moneyline: Colts -125, Patriots +105

Total: O 43 (-110), U 43 (-110) 

Indianapolis Colts

NFL Team Indianapolis ColtsThe Colts are in a crucial position, having lost four of their last six games. They’ve been a better team on the road, winning three of their past four away games. Quarterback Gardner Minshew has been consistent, with a 63.6% pass completion rate, throwing for 1,527 yards, and eight touchdowns. Receivers Michael Pittman Jr. and Josh Downs have been his top targets, contributing significantly to the team’s average of 123.3 rushing yards per game. However, the Colts have struggled to maintain their favorite status, especially against AFC opponents, failing to cover the spread in recent matches.

New England Patriots

NFL Team New England PatriotsOn the other side, the Patriots are also in a rough patch, losing five of their last six games. Quarterback Mac Jones has completed 64.8% of his passes and has a higher touchdown count than Minshew, but also a higher interception rate. Despite their decent passing game, the Patriots’ ground game lags, with an average of 86.9 yards per game. They’ve shown vulnerabilities against teams with losing records and have a history of not covering the spread as underdogs.


Defensively, both teams have their weaknesses, with the Colts allowing more points on average, but they have shown they can put up points, making them a formidable offense that looks like a top 10 in the league, even without talented rookie QB Anthony Richardson. The Patriots, however, have struggled offensively, particularly with finishing drives, scoring 17 or fewer points in most of their recent games. With the Colts aiming to stay in playoff contention, they have a compelling reason to seek a win.

This anticipation sets the stage for an intriguing contest, where the Colts, with their robust offense, might just have the upper hand against the Patriots, who are struggling to find their rhythm. Bettors eyeing this game should consider these dynamics, as the Colts look to capitalize on the Patriots’ offensive challenges to secure a much-needed victory. Bet on the Colts to cover the -1.5 spread on BUSR NFL Odds