NFL Week 7 Early Odds: The Betting Guide for Every Game on the Slate
Welcome back, football fans and savvy bettors! The NFL season is in full swing, and with six weeks behind us, Week 7 offers another fresh slate of opportunities. Injuries, momentum swings, and stunning upsets continue to reshape the landscape, especially with several key divisional matchups on the calendar. This is where value bets emerge, narratives evolve, and sharp bettors can get an edge.
From Thursday Night Football‘s AFC North rivalry showcase to a Sunday London tilt and a high-total battle on Monday Night Football, the Week 7 schedule is stacked. Below, you’ll find early odds for every game and smart betting angles to keep in mind. Let’s dive in.
Thursday Night Football, Oct. 16
Pittsburgh Steelers at Cincinnati Bengals
| Team | Spread | Moneyline (ML) | Total (Over/Under) |
| Steelers | -5.5 | -260 | 42.5 |
| Bengals | +5.5 | +195 | 42.5 |
Betting Angle
This is a pivotal AFC North clash. The Steelers are road favorites, a sign of confidence from oddsmakers given their strong start. The line has already climbed from an opener of -4.5, suggesting sharp money is on Pittsburgh. The total is low, reflecting the likelihood of a defensive battle where both teams rely on their running games. Lean Steelers -5.5 to cover, trusting their defense and the Bengals’ offensive struggles. The Under 42.5 also looks appealing given the divisional stakes and potential for a conservative game plan.
Sunday Slate, Oct. 19
Los Angeles Rams at Jacksonville Jaguars (in London)
| Team | Spread | Moneyline (ML) | Total (Over/Under) |
| Rams | -3 | -155 | 44.5 |
| Jaguars | +3 | +121 | 44.5 |
Betting Angle
The Rams are laying a field goal in the UK. International games can be unpredictable, but the line suggests the Rams are the marginally better team. The spread has moved down from an opener near -4.5 for the Rams, so there may be better value in betting the Jaguars +3 if you think this will be a tight, low-scoring affair. Given both teams’ recent form, the Over 44.5 is a slight lean if the time zone issues don’t slow down the offensive pace.
Carolina Panthers at New York Jets
| Team | Spread | Moneyline (ML) | Total (Over/Under) |
| Panthers | +1 | -121 | 43 |
| Jets | -1 | -105 | 43 |
Betting Angle
Remarkably, the winless Jets are slight home favorites. The line opened higher for New York but has shifted toward Carolina, suggesting sharp money likes the Panthers. Carolina is coming off an outstanding offensive performance in Week 6. Given the Jets’ offensive turmoil and the Panthers’ momentum, taking the Panthers +1 or even the Panthers ML (-121) offers good value. The total is middle-of-the-road; consider the Under 43 if the Jets’ offense remains stagnant.
New England Patriots at Tennessee Titans
| Team | Spread | Moneyline (ML) | Total (Over/Under) |
| Patriots | -7 | 42.5 | |
| Titans | +7 | 42.5 |
Betting Angle
The Patriots are heavily favored on the road against a Titans team that’s struggled. The spread of -7 is a tricky spot, close to the key number of seven. If you believe the Titans’ defense can keep them in the game, Titans +7 is the play. The low total suggests oddsmakers don’t expect much scoring, making the Under 42.5 a solid consideration, especially if Tennessee’s defense travels well.
Miami Dolphins at Cleveland Browns
| Team | Spread | Moneyline (ML) | Total (Over/Under) |
| Dolphins | +2.5 | +116 | 40.5 |
| Browns | -2.5 | -148 | 40.5 |
Betting Angle
This is one of the lowest totals on the slate, pointing toward a slugfest dominated by defense and the ground game. The Browns are slight home favorites. The line of -2.5 is respectable, but if Tua Tagovailoa and the Dolphins’ offense are close to full strength, taking the points on a talented team like Miami is tempting. Lean Over 40.5 as a contrarian play, betting on offensive breakouts against the defensive grind.
New Orleans Saints at Chicago Bears
| Team | Spread | Moneyline (ML) | Total (Over/Under) |
| Saints | +5.5 | +189 | 45.5 |
| Bears | -5.5 | -250 | 45.5 |
Betting Angle
The Bears are the favorites here, suggesting their recent momentum is outweighing the Saints’ potential. A spread of -5.5 is significant for a team that has historically struggled to cover this number. If the Saints can limit turnovers and rely on their run game, they could cover. The total of 45.5 is moderate—Lean Under 45.5 if you expect a tighter, more defensive game from both clubs.
Philadelphia Eagles at Minnesota Vikings
| Team | Spread | Moneyline (ML) | Total (Over/Under) |
| Eagles | -2.5 | -139 | 42.5 |
| Vikings | +2.5 | +109 | 42.5 |
Betting Angle
The Eagles are modest road favorites after their first loss in Week 6. The line has moved from an opener of Eagles -1.5, showing market support. The Vikings are coming off a bye and may have a key QB returning, adding uncertainty. The Eagles -2.5 is manageable if their offense regains its efficiency. The total is low for an Eagles game; the Over 42.5 might be a worthwhile play, betting on a motivated Philly offense.
Las Vegas Raiders at Kansas City Chiefs
| Team | Spread | Moneyline (ML) | Total (Over/Under) |
| Raiders | +12.5 | +510 | 45.5 |
| Chiefs | -12.5 | -847 | 45.5 |
Betting Angle
This is the biggest spread on the board, showing immense confidence in the Chiefs at home. Divisional games can be closer than expected, but covering double digits is tough. The total is modest for a Chiefs game. Lean Raiders +12.5, hoping for a backdoor cover in what is likely a Chiefs win. The Over 45.5 is tempting, especially if the Chiefs jump out to an early lead.
New York Giants at Denver Broncos
| Team | Spread | Moneyline (ML) | Total (Over/Under) |
| Giants | +7 | +260 | 40 |
| Broncos | -7 | -360 | 40 |
Betting Angle
The Broncos are laying exactly a touchdown at home. The Giants are coming off a surprising win, while the Broncos are returning from an international game. The line of -7 is a key number. Lean Under 40, as both teams boast strong defenses and inconsistent offenses, making points hard to come by. Giants +7 is a plausible cover if the Broncos are sluggish returning from their London trip.
Indianapolis Colts at Los Angeles Chargers
| Team | Spread | Moneyline (ML) | Total (Over/Under) |
| Colts | +1.5 | -101 | 48.5 |
| Chargers | -1.5 | -128 | 48.5 |
Betting Angle
This is one of the tightest spreads of the week, a pick’em with a slight edge to the home team. The high total suggests an offensive showcase. Lean Chargers -1.5 based on the superior quarterback play and recent performance. The Over 48.5 is the top bet here, expecting a fast-paced game with scoring from both sides.
Washington Commanders at Dallas Cowboys
| Team | Spread | Moneyline (ML) | Total (Over/Under) |
| Commanders | -2.5 | -148 | 54 |
| Cowboys | +2.5 | +116 | 54 |
Betting Angle
The Commanders are slight road favorites in this high-scoring divisional affair. The total of 54 is the highest on the main slate, a considerable number for a reason. Lean Over 54, as both teams have shown they can put up points and struggle on defense at times. Taking the Cowboys +2.5 is an appealing underdog play at home in a classic rivalry game.
Green Bay Packers at Arizona Cardinals
| Team | Spread | Moneyline (ML) | Total (Over/Under) |
| Packers | -6.5 | -310 | 44.5 |
| Cardinals | +6.5 | +226 | 44.5 |
Betting Angle
The Packers are near-touchdown road favorites. Green Bay’s offense has been impressive, but Arizona has been scrappy. The Packers -6.5 is a reasonable bet if you expect their high-powered offense to dominate. The total is reasonable, and the under 44.5 could be in play if the Cardinals struggle to keep pace and slow the game down.
Sunday Night Football, Oct. 19
Atlanta Falcons at San Francisco 49ers
| Team | Spread | Moneyline (ML) | Total (Over/Under) |
| Falcons | +3 | +135 | 46 |
| 49ers | -3 | -173 | 46 |
Betting Angle
This NFC matchup sees the 49ers as field-goal favorites at home. The line is fair, reflecting the 49ers’ overall strength. The total is in the middle range. If the 49ers’ defense can force turnovers, 49ers -3 is a solid bet. However, if the Falcons’ potent rushing attack can control the clock, taking the Falcons +3 is advisable. Lean under 46 for a game that might be controlled on the ground.
Monday Night Football Doubleheader, Oct. 20
Tampa Bay Buccaneers at Detroit Lions
| Team | Spread | Moneyline (ML) | Total (Over/Under) |
| Buccaneers | +4.5 | +170 | 52.5 |
| Lions | -4.5 | -234 | 52.5 |
Betting Angle
Another high-total game, indicating an expected offensive showcase in Detroit. The Lions are favored by more than a field goal. Lions -4.5 is a solid bet given their dominance at home this season. The Over 52.5 is the top betting angle, as both offenses are capable of high scoring, and the dome environment encourages a faster pace.
Houston Texans at Seattle Seahawks
| Team | Spread | Moneyline (ML) | Total (Over/Under) |
| Texans | +3 | +141 | 41 |
| Seahawks | -3 | -190 | 41 |
Betting Angle
The Seahawks are laying a field goal at home against a scrappy Texans team. The total is relatively low for a modern NFL game, reflecting faith in both defenses. The line has stayed put at the key number of three—lean Texans +3, expecting them to keep the game close. However, the Under 41 is the strongest play, betting on two disciplined defenses and a ground-focused, clock-controlling game.
Betting Strategy Tips
- Line Movement Matters: Early lines often shift. Jump on favorable spreads like Steelers -5.5 or Panthers +1 now before the market adjusts.
- Watch Injuries & Weather: Late-week news, especially for quarterbacks or key defensive players, can drastically affect totals or spreads.
- Matchup Leverage: Target games where one team’s strength aligns with the opponent’s weakness (e.g., the Lions’ offense against a struggling defense for the Over 52.5).
- Totals Equity: The high totals (like the two above 53) and the very low totals (like the 40 in the Dolphins/Browns game) offer the best Over/Under opportunities this week.
- Bankroll Discipline: High spreads (e.g., Chiefs -10.5) or tight lines (e.g., Colts/Chargers) can be tempting—size your bets accordingly.
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