NFL Week 18 Betting Odds & Best Matchups
NFL Week 18 is not about trends, narratives, or what happened last Sunday. This is the sharpest betting week of the NFL season because motivation is no longer a guess. Division titles, playoff seeding, and win-or-go-home spots create urgency that moves lines fast and rewards bettors who act early.
Below is a full breakdown of NFL Week 18 matchups, with live BUSR odds and the key context you need before kickoff.
Carolina Panthers vs. Tampa Bay Buccaneers
Kickoff: 01/03 – 3:30 PM ET
Division implications drive this matchup. Tampa Bay plays at home with postseason positioning on the line, while Carolina enters as a live underdog.
| Team | Spread | Moneyline | Total |
|---|---|---|---|
| Carolina Panthers | +2.5 (-105) | +123 | O 43.5 (-110) |
| Tampa Bay Buccaneers | -2.5 (-115) | -151 | U 43.5 (-110) |
Seattle Seahawks vs. San Francisco 49ers
Kickoff: 01/03 – 7:00 PM ET
One of the most meaningful games of the week. Seattle and San Francisco close the season with division seeding at stake in a true prime-time spot.
| Team | Spread | Moneyline | Total |
|---|---|---|---|
| Seattle Seahawks | -1.5 (-110) | -122 | O 48 (-110) |
| San Francisco 49ers | +1.5 (-110) | -101 | U 48 (-110) |
New Orleans Saints vs. Atlanta Falcons
Kickoff: 01/04 – 12:00 PM ET
Both teams finish the season with one last divisional matchup. Motivation is straightforward, and line value reflects a tight game.
| Team | Spread | Moneyline | Total |
|---|---|---|---|
| New Orleans Saints | +3.5 (-110) | +147 | O 44 (-110) |
| Atlanta Falcons | -3.5 (-110) | -190 | U 44 (-110) |
Dallas Cowboys vs. New York Giants
Kickoff: 01/04 – 12:00 PM ET
Dallas enters as the favorite in a classic NFC East matchup. This game presents opportunities across spreads and totals depending on game flow.
| Team | Spread | Moneyline | Total |
|---|---|---|---|
| Dallas Cowboys | -3.5 (-110) | -202 | O 51.5 (-110) |
| New York Giants | +3.5 (-110) | +155 | U 51.5 (-110) |
Cleveland Browns vs. Cincinnati Bengals
Kickoff: 01/04 – 12:00 PM ET
Cincinnati closes the year as a heavy favorite, while Cleveland enters as a sizable underdog.
| Team | Spread | Moneyline | Total |
|---|---|---|---|
| Cleveland Browns | +7.5 (-110) | +285 | O 44.5 (-110) |
| Cincinnati Bengals | -7.5 (-110) | -400 | U 44.5 (-110) |
Indianapolis Colts vs. Houston Texans
Kickoff: 01/04 – 12:00 PM ET
Houston controls the matchup, and the market reflects it. This is one of the largest spreads on the Week 18 board.
| Team | Spread | Moneyline | Total |
|---|---|---|---|
| Indianapolis Colts | +10.5 (-110) | +440 | O 39 (-110) |
| Houston Texans | -10.5 (-110) | -699 | U 39 (-110) |
Tennessee Titans vs. Jacksonville Jaguars
Kickoff: 01/04 – 12:00 PM ET
Jacksonville closes the season as a strong home favorite with one of the week’s highest moneyline prices.
| Team | Spread | Moneyline | Total |
|---|---|---|---|
| Tennessee Titans | +13.5 (-110) | +540 | O 47.5 (-110) |
| Jacksonville Jaguars | -13.5 (-110) | -952 | U 47.5 (-110) |
Green Bay Packers vs. Minnesota Vikings
Kickoff: 01/04 – 12:00 PM ET
Minnesota is heavily favored at home as Green Bay enters as a live underdog.
| Team | Spread | Moneyline | Total |
|---|---|---|---|
| Green Bay Packers | +7 (-110) | +270 | O 35.5 (-110) |
| Minnesota Vikings | -7 (-110) | -370 | U 35.5 (-110) |
Los Angeles Chargers vs. Denver Broncos
Kickoff: 01/04 – 3:25 PM ET
Denver is priced as one of the strongest favorites on the slate, with a large spread and short moneyline.
| Team | Spread | Moneyline | Total |
|---|---|---|---|
| Los Angeles Chargers | +13 (-110) | +600 | O 37.5 (-110) |
| Denver Broncos | -13 (-110) | -1099 | U 37.5 (-110) |
Miami Dolphins vs. New England Patriots
Kickoff: 01/04 – 3:25 PM ET
New England is favored at home, with Miami entering as a double-digit underdog.
| Team | Spread | Moneyline | Total |
|---|---|---|---|
| Miami Dolphins | +10.5 (-110) | +440 | O 45.5 (-110) |
| New England Patriots | -10.5 (-110) | -699 | U 45.5 (-110) |
Kansas City Chiefs vs. Las Vegas Raiders
Kickoff: 01/04 – 3:25 PM ET
Kansas City is favored on the road in a matchup that offers balanced pricing across the board.
| Team | Spread | Moneyline | Total |
|---|---|---|---|
| Kansas City Chiefs | -5.5 (-110) | -265 | O 37 (-110) |
| Las Vegas Raiders | +5.5 (-110) | +199 | U 37 (-110) |
Detroit Lions vs. Chicago Bears
Kickoff: 01/04 – 3:25 PM ET
A tight spread highlights what should be one of the more competitive games of the afternoon window.
| Team | Spread | Moneyline | Total |
|---|---|---|---|
| Detroit Lions | +3 (-110) | +134 | O 50.5 (-110) |
| Chicago Bears | -3 (-110) | -172 | U 50.5 (-110) |
New York Jets vs. Buffalo Bills
Kickoff: 01/04 – 3:25 PM ET
Buffalo closes the regular season as a clear favorite at home.
| Team | Spread | Moneyline | Total |
|---|---|---|---|
| New York Jets | +7 (-110) | +285 | O 38 (-110) |
| Buffalo Bills | -7 (-110) | -400 | U 38 (-110) |
Washington Commanders vs. Philadelphia Eagles
Kickoff: 01/04 – 3:25 PM ET
Philadelphia is favored at home, with Washington positioned as a live underdog.
| Team | Spread | Moneyline | Total |
|---|---|---|---|
| Washington Commanders | +4 (-110) | +163 | O 38.5 (-110) |
| Philadelphia Eagles | -4 (-110) | -212 | U 38.5 (-110) |
Arizona Cardinals vs. Los Angeles Rams
Kickoff: 01/04 – 3:25 PM ET
Los Angeles enters as a strong home favorite to close the season.
| Team | Spread | Moneyline | Total |
|---|---|---|---|
| Arizona Cardinals | +7 (-105) | +265 | O 46 (-110) |
| Los Angeles Rams | -7 (-115) | -370 | U 46 (-110) |
Baltimore Ravens vs. Pittsburgh Steelers
Kickoff: 01/04 – 7:20 PM ET
Week 18 closes with a classic AFC North matchup under the lights.
| Team | Spread | Moneyline | Total |
|---|---|---|---|
| Baltimore Ravens | -3.5 (+100) | -206 | O 41 (-110) |
| Pittsburgh Steelers | +3.5 (-120) | +159 | U 41 (-110) |
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