Eagles vs Giants Predictions for Week 6 Thursday Night Football

NFL
October 8, 2025


The NFL Week 6 slate kicks off with a divisional clash under the lights as the Philadelphia Eagles visit the New York Giants at MetLife Stadium for Thursday Night Football. This matchup holds major significance for bettors following NFL Odds and NFL Betting trends, as Philadelphia looks to bounce back from its first loss of the season while the Giants attempt to recover from a 1-4 start.

The Eagles enter as the reigning NFC champions, sitting at 4-1 after falling 21-17 to the Denver Broncos in Week 5. New York, meanwhile, dropped a 26-14 decision to the New Orleans Saints and continues searching for consistency on both sides of the ball. Kickoff is scheduled for 8:15 PM ET, and we’ll break down the matchup, player props, and key betting insights to help identify the most valuable plays for this primetime divisional showdown.

 

Eagles Look to Rebound After First Loss

 

Bet on Football with the latest news, expert picks and the best NFL Wildcard Games. 🏈 JOIN NOW and win up to $2,500 BONUS 🏈The Philadelphia Eagles saw their four-game win streak snapped against the Denver Broncos, marking their first setback of the 2025 season. Jalen Hurts remains the centerpiece of the offense, throwing for 889 yards and seven touchdowns with a 66.9% completion rate. On the ground, he’s added 182 rushing yards and four scores, continuing to be one of the league’s most dangerous dual-threat quarterbacks.

 

Offense Week 5 Recap

Running back Saquon Barkley has emerged as the focal point of the backfield with 267 rushing yards and three touchdowns, giving Philadelphia balance between the run and pass. DeVonta Smith leads all receivers with 25 catches for 272 yards, while tight end Dallas Goedert has provided red-zone reliability with 15 receptions for 133 yards and four touchdowns. A.J. Brown has also contributed with 19 receptions for 194 yards and one score, giving Hurts multiple dependable options downfield.

 

Defensively Speaking

Defensively, the Eagles continue to play physical, disciplined football. Linebacker Zack Baun leads the unit with 42 total tackles, including 26 solo stops and two sacks. As a group, Philadelphia has recorded seven sacks and three interceptions through five games. The front seven has generated consistent pressure, while the secondary has limited opposing passing efficiency.

Philadelphia remains one of the most efficient red-zone teams in the NFL, converting 92.3% of its opportunities entering Week 6, ranking first in the league. The Eagles’ ability to sustain drives and finish in scoring position has been a major factor in their 4-1 record.

The Eagles have won eight consecutive games against NFC opponents, demonstrating their dominance within the conference. They’ve also covered the spread in seven of their last eight road games, making them a reliable play away from Lincoln Financial Field.

Reigning Super Bowl champions have historically performed well in Week 6 matchups, winning the first quarter and first half in each of their last seven games during this stretch. Philadelphia also has a strong trend in scoring first, finding the end zone first in 13 of their previous 14 games.

 

Eagles to Break the Thursday Night Football Pattern

While Thursday games often produce lower scores, the Eagles have bucked that pattern, with each of their last five Thursday road games going over the total. That could signal potential for offensive rhythm early, particularly if Hurts and Barkley can exploit the Giants’ defensive inconsistencies.

Jalen Hurts has recorded 25+ completions in four of his last five October road games and 236+ passing yards in nine of his previous 10 October contests. He’s also scored two or more total touchdowns in three of his last four road games against losing teams.

Dallas Goedert has been consistent in October, surpassing 36 receiving yards in each of his last six road appearances.

Tank Bigsby could play an expanded role, having recorded 28+ rushing yards in nine of his last 11 games versus conference opponents.

With a favorable matchup against a struggling Giants defense, Philadelphia’s offensive playmakers could have productive nights for prop bettors.

 

Giants Searching for Stability

 

NFL Team New York GiantsThe New York Giants enter Week 6 at 1-4, looking to regroup after a 26-14 loss to the Saints. Rookie quarterback Jaxson Dart continues to show flashes of potential, throwing for 313 yards, three touchdowns, and two interceptions on 65% passing. However, the offense has struggled to find consistency, particularly following the season-ending injury to Malik Nabers, who led the team with 271 receiving yards and two touchdowns.

 

Offensive Line Struggles

Running back Cam Skattebo has been a bright spot with 240 rushing yards and two touchdowns, providing physicality and short-yardage reliability. Wideout Wan’Dale Robinson has stepped up in Nabers’ absence with 23 receptions for 267 yards and a touchdown. Darius Slayton has also contributed 166 receiving yards, though the passing game has lacked explosiveness in recent weeks.

 

Giants’ Defensive Analysis

Defensively, linebacker Bobby Okereke anchors the unit with 48 total tackles, including 23 solo. Cornerback Paulson Adebo has added 37 tackles, with 32 solo stops, showing strong coverage ability. Edge rusher Brian Burns continues to be the team’s primary disruptor, leading New York with five sacks. Collectively, the Giants have tallied 10 sacks and three interceptions, with a defensive line that has pressured opposing quarterbacks effectively despite inconsistent coverage behind them.

The Giants rank first in the league in fourth-down attempts (14), showing a willingness to take risks, but their red-zone execution has been their downfall. Entering Week 6, New York sits dead last in red-zone scoring percentage (31.6%), a major issue when facing a team as efficient as Philadelphia.

MetLife Stadium has been kind to the Giants in recent history, as the home team has won seven of their last eight games. The home team has also covered the spread in five of the Eagles’ last six Week 6 games, giving some support to New York bettors.

The Giants have won the first quarter in three of their last four games as underdogs and scored the first touchdown in four straight contests. Additionally, the home team has won the first half in five of the last six meetings between the Eagles and Giants, indicating early competitiveness even in losses.

New York’s Thursday Night Football record is stronger than expected, with each of its last eight home games in October going under the total points line, a factor worth considering in over/under markets.

Theo Johnson has scored in each of his last two games and topped 33 receiving yards in six of his previous seven appearances versus NFC opponents.

Devin Singletary has exceeded 43 rushing and receiving yards combined in each of his last four Week 6 appearances and recorded 18+ rushing yards in 10 consecutive October home games.

For prop bettors, Singletary and Johnson present viable low-yardage plays in a conservative Giants offensive system.

 

Week 6 Thursday Night Football Match Betting Analysis and Prediction

 

This Week 6 matchup features a clear statistical contrast. Philadelphia ranks first in red-zone conversion rate (92.3%), while New York ranks last at 31.6%. The Eagles’ balanced offense and defensive pressure give them a clear edge in efficiency.

The Giants have shown aggression on fourth down, but those decisions haven’t translated into points. Meanwhile, Philadelphia has displayed resilience, coming back from a 19-point deficit against the Los Angeles Rams, the largest comeback in the league this season.

Special teams could also play a significant role in this game. Eagles punter Braden Mann ranks second in the NFL with a 52.5-yard gross average per punt, a key field position weapon in a matchup likely to hinge on turnovers and short fields.

The Eagles have historically dominated this rivalry, covering the spread in seven of their last eight road games. Their efficiency inside the red zone and depth on both sides of the ball make them a stronger overall team.

Philadelphia’s recent loss to Denver should sharpen focus entering Thursday Night Football, especially for Jalen Hurts, who has excelled on the road against sub-.500 opponents. With Barkley providing balance and the defense capable of forcing Dart into mistakes, Philadelphia is well-positioned to win by a touchdown or more.

The Giants’ injuries and red-zone inefficiency make it difficult to trust them in sustained drives. Expect the Eagles’ pass rush to consistently pressure Dart, creating turnovers that tilt the field position and tempo in Philadelphia’s favor.

Divisional Thursday games often trend toward the under, and this matchup fits that profile. While Philadelphia has offensive firepower, short rest and conservative game scripts typically lead to fewer possessions. The Giants’ offense has yet to show the capability to sustain drives, especially against top-tier defenses.

New York’s recent home trends support a low-scoring projection; each of their last eight October home games has gone under the total. Combine that with a struggling passing attack and two defenses capable of limiting explosive plays, and the under provides solid value at 40.5.

 

Best picks:  Spread Pick: Philadelphia Eagles -7 (-120), Under 40.5 (-110) 

 

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