Arizona Cardinals Odds

How to Bet the Arizona Cardinals

The Arizona Cardinals enter 2026 in a full rebuild after a 3-14 season ended the Kyler Murray era, with the former No. 1 overall pick released in March following a foot injury that limited him to five games. Mike LaFleur takes over as head coach after three seasons as the Rams’ offensive coordinator, replacing Jonathan Gannon. Jacoby Brissett, who went 3,366 yards with 23 touchdowns filling in for an injured Murray last season, is the presumed starter, with third-round rookie Carson Beck developing behind him. Running back James Conner’s season-ending injury after just three games was a major factor in the 2025 collapse, and the Cardinals used the No. 3 overall pick on Notre Dame running back Jeremiyah Love to rebuild the backfield. Arizona opens at +50000 to win Super Bowl LXI and +6000 to win the NFC West at BUSR.ag, the longest odds in the league.
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Arizona Cardinals 2026 Betting Odds

Super Bowl LXI+50000Longest odds in the NFL
Win NFC+20000Conference champion odds
Win Total Over+151Over 4.5 wins at BUSR
Win Total Under-187Under 4.5 wins at BUSR
2025 Record3-14Last in NFC West
Win NFC West+6000Longest price in the division

Odds via BUSR.ag, updated daily. All Cardinals markets live at BUSR.

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Arizona Cardinals 2026 Schedule

WeekMatchTime (ET)
September 2026
Wk 1at Los Angeles Chargers
SoFi Stadium, Inglewood CA • CBS
Sun Sept 13, 4:25 PM
Wk 2vs. Seattle Seahawks (Home Opener)
State Farm Stadium, Glendale AZ • FOX
Sun Sept 20, 4:25 PM
Wk 3at San Francisco 49ers
Levi’s Stadium, Santa Clara CA • FOX
Sun Sept 27, 4:05 PM
October 2026
Wk 4at New York Giants
MetLife Stadium, East Rutherford NJ • CBS
Sun Oct 4, 1:00 PM
Wk 5vs. Detroit Lions
State Farm Stadium, Glendale AZ • FOX
Sun Oct 11, 4:25 PM
Wk 6at Los Angeles Rams
SoFi Stadium, Inglewood CA • FOX
Sun Oct 18, 4:05 PM
Wk 7vs. Denver Broncos
State Farm Stadium, Glendale AZ • CBS
Sun Oct 25, 4:05 PM
November 2026
Wk 8at Dallas Cowboys
AT&T Stadium, Arlington TX • FOX
Sun Nov 1, 1:00 PM
Wk 9at Seattle Seahawks
Lumen Field, Seattle WA • FOX
Sun Nov 8, 4:25 PM
Wk 10vs. Los Angeles Rams
State Farm Stadium, Glendale AZ • CBS
Sun Nov 15, 4:05 PM
Wk 11at Kansas City Chiefs
GEHA Field at Arrowhead Stadium, Kansas City MO • CBS
Sun Nov 22, 1:00 PM
Wk 12vs. Washington Commanders
State Farm Stadium, Glendale AZ • FOX
Sun Nov 29, 4:25 PM
December 2026
Wk 13vs. Philadelphia Eagles
State Farm Stadium, Glendale AZ • FOX
Sun Dec 6, 4:05 PM
Wk 14BYE WEEK 
Wk 15vs. New York Jets
State Farm Stadium, Glendale AZ • FOX
Sun Dec 20, 4:05 PM
Wk 16at New Orleans Saints
Caesars Superdome, New Orleans LA • FOX
Sun Dec 27, 11:00 AM
January 2027
Wk 17vs. Las Vegas Raiders
State Farm Stadium, Glendale AZ • CBS
Sun Jan 3, 4:05 PM
Wk 18vs. San Francisco 49ers
State Farm Stadium, Glendale AZ • TBD
TBD Jan 9/10

★ = Key matchup. All times Eastern. Week 18 subject to flexible NFL schedule adjustments. Arizona plays six of its first nine games on the road before finishing with six of its last eight at State Farm Stadium. No primetime games are currently scheduled, though flex scheduling could add one later in the season.

NFC West Division Odds 2026

NFC West: 2026 Division Odds via BUSR.ag
TeamWin NFC West
Rams-105
Seahawks+210
49ers+300
Cardinals+6000

Table reflects confirmed NFC West division-winner odds via BUSR.ag.

Arizona Cardinals Key Players 2026

Jacoby Brissett

Quarterback

Stepped in for an injured Kyler Murray in 2025 and posted 3,366 passing yards with 23 touchdowns despite going just 1-11 as a starter. Now the presumed starter entering 2026 in a contract year, with a new deal reportedly still being worked out.

Carson Beck

Quarterback, Draft Pick

Selected in the third round out of Miami, Beck represents the Cardinals’ long-term developmental option at the position as the team fully resets under Mike LaFleur.

Trey McBride

Tight End

Coming off an All-Pro season, McBride is the cornerstone of the Cardinals’ offense and one of the most productive tight ends in the league regardless of who is under center.

Marvin Harrison Jr.

Wide Receiver

Continues to develop as the Cardinals’ top outside threat, giving the passing game a genuine difference-maker as the quarterback situation sorts itself out.

Jeremiyah Love

Running Back, Draft Pick

The No. 3 overall pick out of Notre Dame steps in to help rebuild a backfield that lost James Conner to a season-ending injury just three games into 2025.

Budda Baker

Safety

Remains the veteran anchor of the Cardinals’ defense, providing leadership and playmaking ability as the roster undergoes a significant reset around him.

Arizona Cardinals 2026 Season Preview

The 2026 Cardinals are starting over almost entirely, from the head coach to the quarterback room, after a 3-14 season that ended the Kyler Murray era in Arizona. Mike LaFleur inherits a roster with real pieces on offense in Trey McBride and Marvin Harrison Jr., but a genuinely unresolved quarterback situation and a defense in need of rebuilding.

2025 Season Review

Arizona finished 3-14, last in the NFC West. Kyler Murray missed 12 games with a foot injury, and running back James Conner’s season-ending injury after three games compounded the offensive collapse. Jacoby Brissett took over and posted respectable individual numbers despite a 1-11 record as a starter.

The Kyler Murray Release

Arizona released Murray in March, ending seven tumultuous seasons that began with the No. 1 overall pick in 2019. The Cardinals absorbed a significant dead cap hit rather than risk further guarantees, and the release was reportedly Murray’s own preferred outcome.

The Mike LaFleur Hire

LaFleur replaces Jonathan Gannon after three seasons as the Rams’ offensive coordinator. He inherits a roster that finished with the league’s worst or near-worst record and a quarterback competition that remains genuinely unsettled entering the season.

Key Offseason Additions

Edge Josh Sweat (FA, from Philadelphia, Super Bowl winner), RB Jeremiyah Love (Draft, No. 3 overall), QB Carson Beck (Draft, Rd 3). The moves targeted both immediate defensive help and a long-term answer at quarterback.

Offensive Outlook

Trey McBride and Marvin Harrison Jr. give Arizona real weapons regardless of who starts at quarterback. Jacoby Brissett’s ability to build on his 2025 production, and Jeremiyah Love’s rookie transition, will shape the offense’s overall ceiling.

Defensive Outlook

Josh Sweat, BJ Ojulari and rookie Walter Nolen III give the Cardinals real building blocks on the defensive line. Budda Baker remains the veteran anchor as Mike LaFleur’s staff installs new schemes across the roster.

2026 Season Verdict

Arizona enters 2026 as one of the league’s clearest rebuild candidates, and the win total at 4.5 with the Under favored at -187 reflects a market that expects continued struggles during the transition. Best bet: track the Brissett-Beck quarterback situation closely through camp, since real offensive improvement depends heavily on stability at the position.

How to Bet the Arizona Cardinals in 2026

Every Cardinals bet at BUSR falls into one of these core markets. Here is how each one works with real 2026 Cardinals examples.

Point Spread

The Cardinals are assigned a number reflecting how much better or worse they are than the opponent. As underdogs in most matchups, expect Arizona to be priced with a plus number in the majority of its games.

Cardinals spread at Chargers (Week 1). Bet the spread once BUSR posts the line closer to kickoff.
Moneyline

Pick the Cardinals to win outright with no spread. A positive number means Arizona is the underdog, and a $100 bet wins more than $100.

Cardinals moneyline at Chargers, Week 1. Check BUSR for the current line as the LaFleur era begins.
Totals (Over/Under)

Bet on the combined score of both teams. No individual team performance matters, only the final combined score against the posted number.

Cardinals at Chargers, Week 1. Target the total based on how Jacoby Brissett and the offense look in the season opener.
Futures

Bet on Cardinals season-long outcomes. Super Bowl winner, win total, and more once NFC West division odds are confirmed. Odds are longest now and shorten as Arizona wins games.

Cardinals Over 4.5 wins at +151. A $100 bet returns $251 if Arizona wins 5 or more games.
Parlays

Combine two or more Cardinals bets into one ticket for a bigger payout. All legs must win. A Cardinals spread plus a Trey McBride receiving yards Over is a classic same-game parlay.

Cardinals ML + Trey McBride Over 55.5 receiving yards. A 2-leg -110 parlay pays roughly +260 on a $100 bet at BUSR.
Player Props

Bet on an individual Cardinals player’s performance in a single game. Most popular: Brissett passing yards, Love rushing yards, McBride receiving yards, Harrison Jr. receiving yards.

Trey McBride Over 55.5 receiving yards. Coming off an All-Pro season, he remains the most consistent weekly target regardless of the quarterback situation.
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Arizona Cardinals Betting Markets at BUSR

Every Cardinals market available at BUSR.ag, from weekly game lines through Super Bowl LXI futures.

MarketWhat You Are Betting OnCardinals Example
Game SpreadCardinals to cover the point spread each week. Posted Tuesday, updated through kickoff.Cardinals spread at Chargers, Week 1.
MoneylineCardinals to win the game outright. No spread involved.Cardinals moneyline at BUSR, updated weekly.
Game TotalCombined points scored by both teams. Over or Under the posted number.Cardinals at Chargers total, Week 1.
Super Bowl FuturesCardinals to win Super Bowl LXI. Longest odds in the league, shortest after they win games.Cardinals +50000 at BUSR.
NFC West WinnerCardinals to finish first in the NFC West over 17 regular season weeks.Cardinals +6000 at BUSR, the longest price in the division.
Win TotalCardinals to finish Over or Under 4.5 wins in the 2026 regular season.Over 4.5 wins at +151. Under 4.5 wins at -187.
Player PropsIndividual performance bets on Cardinals players each week.Brissett Over passing yards. McBride Over receiving yards.
Same-Game ParlayCombine multiple Cardinals bets from the same game into one ticket.Cardinals ML + McBride Over receiving yards + Love Over rushing yards.
Live BettingBet on the Cardinals during the game as the action unfolds. Lines update in real time.Cardinals trailing at halftime. Live moneyline value if the offense finds rhythm.

Arizona Cardinals Player Props 2026

The most popular Arizona Cardinals player prop markets at BUSR.ag for the 2026 season, with sharp angles on each.

PlayerProp MarketSharp Angle
Jacoby BrissettPassing Yards O/UPosted solid individual numbers filling in for an injured Murray in 2025. His full offseason as the presumed starter should mean a more comfortable command of the offense from Week 1.
Trey McBrideReceiving Yards O/UComing off an All-Pro season and the clear focal point of the passing game. The most reliable weekly prop on the roster regardless of the quarterback situation.
Marvin Harrison Jr.Receiving Yards O/UContinues to develop as a genuine outside threat. Worth tracking how his role evolves as the offense adjusts to a new quarterback room.
Jeremiyah LoveRushing Yards O/UThe No. 3 overall pick steps into a backfield that lost James Conner to injury in 2025. His rookie transition is one of the most important storylines of the season.
Josh SweatSacks O/UA key free agency addition from the Super Bowl champion Eagles. Should provide an immediate lift to a Cardinals pass rush in need of playmakers.
Budda BakerTackles O/UThe veteran anchor of the secondary remains one of the most consistent tackling props on the roster as the defense rebuilds around him.
Sharp Betting Angles for 2026: Three Cardinals bets to consider before the season starts. First: track the Brissett-Beck quarterback competition closely through the preseason, since real offensive stability depends on how that situation resolves. Second: Trey McBride’s receiving props remain the most reliable Cardinals market regardless of the quarterback situation, given his All-Pro caliber play. Third: the win total at 4.5, with the Under favored at -187, reflects a market that has fully priced in a rebuild year, making the Over a live long-shot if the new coaching staff generates any early traction.
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New customers only. Min $50 deposit required. Must be 18+. Terms and conditions apply. Please bet responsibly.   •   Check daily for updated NFL odds, lines and spreads.   •   Player props available for every game.   •   Live in-game betting on every NFL matchup.   •   Super Bowl LXI futures live now -- Rams +600.   •   Same-game parlays available at BUSR.

Arizona Cardinals Betting FAQ

Did the Cardinals release Kyler Murray?
Yes. Arizona released Murray in March 2026 after seven seasons, ending an era marked by injuries and unmet expectations. Murray played just five games in 2025 before a foot injury ended his season, and the release was reportedly his preferred outcome.
Who is the Cardinals starting quarterback in 2026?
Jacoby Brissett is the presumed starter after going 3,366 yards with 23 touchdowns, replacing an injured Kyler Murray in 2025. Third-round rookie Carson Beck is also in the mix as the team’s long-term developmental option.
Who is the Cardinals head coach in 2026?
Mike LaFleur is the Cardinals head coach in 2026, hired to replace Jonathan Gannon after a 3-14 season. LaFleur previously spent three seasons as the Rams’ offensive coordinator.
What are the Arizona Cardinals odds to win Super Bowl LXI?
The Cardinals are +50000 to win Super Bowl LXI at BUSR.ag, the longest odds in the league as Arizona begins a full rebuild under new head coach Mike LaFleur.
What are the Cardinals’ odds to win the NFC West in 2026?
The Cardinals are +6000 to win the NFC West at BUSR.ag, the longest price in the division behind the Rams, Seahawks, and 49ers.
What is the Cardinals win total for 2026?
The Cardinals win total at BUSR.ag is 4.5 wins. The Under is priced at -187 and the Over at +151, reflecting the market’s expectation of another difficult season during the rebuild.
What channel are Cardinals games on in 2026?
Cardinals games air on CBS and FOX in 2026. Arizona does not currently have a primetime game scheduled, though flex scheduling could add one later in the season. The team plays six of its final eight games at home.
How do I bet on Arizona Cardinals props at BUSR?
Sign up at BUSR.ag, deposit $50 or more using promo code 300SB1, and navigate to the NFL section. Select the Cardinals game and choose Player Props. You will find Brissett passing yards, Love rushing yards, McBride receiving yards, and Harrison Jr. receiving yards. New members receive a 300% welcome bonus.
Can I bet on the Cardinals live during the game?
Yes. BUSR offers live in-game betting on every Cardinals game throughout 2026. Spreads, moneylines, totals, and player props update in real time. Live value can appear if Arizona falls behind early and the market overreacts before the offense finds rhythm.

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